PainCube AI Pain Management Platform

What if we could predict pain 30⁠–⁠60 minutes before onset?

We aim for a world where no pain goes untreated.

PainCube CDSS dashboard showing real-time pain-index monitoring at the bedside

Stop asking patients, ‘How much does it hurt?’

We ask the body through objective biosignals, not self-report.

PainCube measures pain on a 0–10 scale from biosignals, predicts onset 30⁠–⁠60 minutes ahead, and provides data-driven analgesic dosing decision support.

01Why PainCube

PainCube focuses on the pain that has long gone unaddressed.

In clinical practice, 80% of patients do not receive adequate pain management.

  • No objective way to measure pain

    And no precise standard for analgesic dosing

  • Pain assessed by subjective self-report

    Measured against imprecise criteria

  • Analgesics prescribed by clinician intuition

Pain management failure rate of 80% shown beside an unresponsive ICU patient

02How PainCube Works

PainCube Solution Overview

  1. PainCube wearable sensor module

    01

    Sensor

    A sensor that attaches at various sites per patient: chest, upper arm, wrist.

  2. PainCube AI engine processing ICU biosignals

    02

    AI

    ICU noise removal; pre-onset pain prediction from biosignal and pain patterns.

  3. Clinician reviewing the PainCube CDSS dashboard

    03

    CDSS

    Dashboard-based pain alerts and dosing support, cutting clinician resource by 80%.

03PainCube Sensor + Data

Multimodal biosignal & clinical data collection

12+ biosignals and medical records collected across Johns Hopkins (32 beds) and Korea University Anam Hospital (24 beds).

  • IRB Approved
  • IRB Approved

Data source

Wear type

  • Upper-arm patch
  • Wrist band
  • Chest patch

Biosignal data (6+)

  • ECG
  • PPG
  • SpO₂
  • Respiration rate
  • Heart rate
  • Temperature

Patient-record data (6+)

  • Age·Sex
  • Diagnosis
  • Surgery info
  • Pain score (NRS)
  • Medication
  • Analgesic administration record
PainCube sensor attached to an ICU patient collecting biosignals at the bedside

04TCAtt-PainNetPain Quantification & Prediction AI

Pain quantification and 30⁠–⁠60 min pre-onset prediction

  • Learns pre-onset biosignal patterns

    And pain-reduction patterns after a dose

  • Produces a 0–10 pain index (CPI)

    Predicts onset 30⁠–⁠60 min in advance

  • Secures the golden time to respond

    Time for clinicians to prescribe and administer analgesics

TCAtt-PainNet engine screen showing the predicted pain index and recommended action

05DDCAESignal Denoising AI

Pure pain-signal extraction via an AI denoising algorithm

  • Encoder-decoder architecture

    Exploits the regularity of pain against irregular noise

  • Removes noise mistaken for pain

    ECMO operation, body motion, and similar artifacts

  • Extracts pure pain signals

    Reduces false alarms and raises prediction accuracy

DDCAE noise-removal engine separating pain signals from ICU noise on a bedside monitor

06CDSSClinical Decision Support System

Data-driven pain management and analgesic dosing

  • Alerts 30⁠–⁠60 min before pain onset

    Secures the golden time to respond

  • Data-driven analgesic dosing decisions

    Includes drug type, timing, and dose

  • Real-time patient monitoring dashboard

    Supports patient-tailored pain management

Clinician using the PainCube CDSS dashboard for real-time patient monitoring

07Clinical Impact

80% less clinician time and cost

  • Before adoption: 34 min per patient

    Pain management time for a single patient

    *Based on a 12-hour shift (SCCM PADIS 2018; Gélinas et al., 2006)

  • After adoption: 7 min per patient

    An 80% reduction in pain management time

    *Routine rounds, pain assessment and dosing greatly streamlined

  • Establishes the adoption rationale for hospitals

    Backed by time and cost savings

Bar chart: pain-management time falling from 34 minutes to 7 minutes, 80% less

Live Demo

See PainCube in action

PainCube live demo preview Open live demo ↗

Team

One team of clinicians and technology professionals

Clinicians and engineers from Johns Hopkins, Korea University Anam Hospital, and StellarCube.

  • Portrait of Jin-Sub Noh, CEO Co-Founder

    Jin-Sub Noh

    CEO

    Professor, AI Application, Hansung University

  • Portrait of Ki-Won Kim, CTO Co-Founder

    Ki-Won Kim

    CTO

    22+ years leading service development across AI, healthcare, senior care, gaming, and portals

  • Portrait of Chang-Won Lim, CSO Co-Founder

    Chang-Won Lim

    CSO

    17+ years in data & AI strategy; led global R&D projects exceeding KRW 1B

  • Portrait of Prof. Hee-Jung Kim, Head of StellarCube AI Medical Center Co-Founder

    Prof. Hee-Jung Kim

    Head of StellarCube AI Medical Center · Prof. of Thoracic Surgery, Korea University

  • Portrait of Prof. Sung-Min Cho, Professor of Neurosurgery at Johns Hopkins University

    Prof. Sung-Min Cho

    Prof. of Neurosurgery, Johns Hopkins University

  • Portrait of Sangmyung Hong, Project Manager

    Sangmyung Hong

    Project Manager

    4+ years in AI product management and data engineering · ex-Naver Cloud

Request IR materials for PainCube

Korean & English IR available. We'll follow up by email.